Double CD38−/CD138− negative multiple myeloma
نویسندگان
چکیده
منابع مشابه
Multiple Myeloma Update
This literature review presents the most recent developments in the management of multiple myeloma, which is characterized by the presence of abnormal plasma cells (myeloma cells) that accumulate into the bone marrow. Aspects related to pathophysiology, clinical manifestations, laboratory, study and treatment are described. These pieces of information are necessary to accomplish a better ...
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Les traitements classiques de myelome multiple et les schemas differents proposes ont ete mis en revue. La poly chimiotherapie de la maladie avec une com-binaison de cyclophosphamide, B.C.N.U. Alkeran, Perdnisone et Vincristine a donnee une meilleur Resultat ceci surtout dans les formes graves et rapidement progressive de la maladie. D'autres sehemas therapeutiques sont en cours.
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Extramedullary plasmacytoma occurs in 18% of patients with multiple myeloma. Laryngeal involvement in multiple myeloma is rare, and only a few cases have been reported. We present a case of a 44-year-old women with multiple myeloma who presented with stridor due to a mass involving the larynx which was initially proven to be plasmacytoma on biopsy. She had evidence of multiple myeloma of IgA la...
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CD45, the first receptor-like protein tyrosine phosphatase expressed on all nucleated hematopoietic cells, is a critical regulator of signaling thresholds in immune cells. Perturbation of its function may contribute to autoimmunity, immunodeficiency and malignancy. The expression of CD45 declines in vivo during normal plasma cell (PC) differentiation. Indeed, CD45 is brightly expressed in norma...
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The association of sarcoidosis with multiple myeloma is not well known. Including this case report, 12 cases of patients with both sarcoidosis and multiple myeloma have been reported in the literature. The skeletal lesions of both conditions have many clinical and radiological similarities, and unless clinicians are aware of the association and the possibility of dual pathologies, the diagnosis...
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ژورنال
عنوان ژورنال: Hematology/Oncology and Stem Cell Therapy
سال: 2019
ISSN: 1658-3876
DOI: 10.1016/j.hemonc.2017.08.003